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Dr. Michael Pikaart has been working at Hope since 1999. 

Teaching expertise

• Allied health/non-majors chemistry (lecture and lab)
• General chemistry (lecture and lab)
• Biochemistry (lecture and lab)
• First-year seminar

See Dr. Pikaart's current research 

AREAS OF INTEREST

• Environmental micobiology
• Research-based pedagogy in biochemistry
• Protein-DNA interactions in gene regulation

EDUCATION

• Ph.D., biological chemistry, The University of Michigan, 1992
• B.S., chemistry, Calvin College, 1986

Grants

• Five years of current continuous NSF-IUSE funding, 2015-2020 亚洲色吧淩ole of Undergraduate Biochemistry Education in Protein Function Assignment亚洲色吧�
• NIH, 亚洲色吧淪pecificity of the Interaction Between Gata-1 and DNA,亚洲色吧� 2003亚洲色吧�2010

Memberships and affiliations

Michael has membership in the American Society for Biochemistry and Molecular Biology, where he is involved in programs in education and professional development.

He has worked for various organizations and community activities, including an American Chemical Society group (NSF-funded workshop) on 亚洲色吧淢olecular Basis of Life Processes亚洲色吧� initiative, serving as poster presentation judge at national ASBMB meetings, volunteering as a Science Olympiad coach, and being a Grand Awards Judge (Molecular and Cellular Biology) for the Intel Science and Engineering Fair in Albuquerque, New Mexico (May 2007). 

Community Service

• Board of Directors, Pediatric Oncology Resource Team (PORT), Helen DeVos Children亚洲色吧檚 Hospital (Grand Rapids, Michigan), 2014亚洲色吧損resent (currently president)
• Volunteer, Child Life, Helen DeVos Children亚洲色吧檚 Hospital, 2014亚洲色吧損resent

Published Works

• 亚洲色吧淐UREs: Building communities to support and sustain protein biochemistry research in the teaching laboratory,亚洲色吧� ASBMB Transforming Undergraduate Education in the Molecular Life Sciences symposium, Tampa Florida (oral presentation), July 20亚洲色吧�23, 2017
• 亚洲色吧淭houghts on MOOCs,亚洲色吧� with J. Provost, ASBMB Today 13(2), 2014
• 亚洲色吧淭he turn of the screw: an exercise in protein structure,亚洲色吧� Biochemistry and Molecular Biology Education 39(3), 2011
• 亚洲色吧淭hermodynamic exploration of eosin-lysozyme binding,亚洲色吧� with A.J. Huisman, L.R. Hartsell and B.P. Krueger, Journal of Chemical Education 87(3), 2010
• 亚洲色吧淗2B ubiquitylation plays a role in nucleosome dynamics during transcription elongation,亚洲色吧� Molecular Cell, 31, 2008
• 亚洲色吧淪ubstitution of DNA-Contacting Amino Acids with Functional Variants in the Gata-1 Zinc Finger: A Structurally and Phylogenetically Guided Mutagenesis,亚洲色吧� Biochemical and Biophysical Research Communication, 369, 2008
• 亚洲色吧淪pectroscopic determination of the thermodynamics of the interation of Pb2+ with GATA proteins,亚洲色吧� Journal of the American Chemical Society, 127, 2005
• 亚洲色吧淎 molecular dissection of the interaction between the transcription factor Gata-1 zinc finger and DNA," Biochemical and Biophysical Research Communications, 316, 2004
• 亚洲色吧淧osition-effect protection and enhancer blocking by the chicken beta-globin insulator are separable activities,亚洲色吧� Proc Natl Acad Sci USA, 99(10), 2002
• "Structural and functional conservation at the boundaries of the chicken beta-globin domain," EMBO, Journal 19(10), 2000
• "The role of histone acetylation and DNA methylation in the maintenance of the imprinted expression of the H19 and Igf-2 genes," FEBS Letters, 458, 1999
• "Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone acetylation, and is prevented by insulators," Genes and Development, 12, 1998
• "Expression and codon usage optimization of the erythroidspecific transcription factor cGATA-1 in baculoviral and bacterial systems," Protein Expression and Purification, 8, 1996