Dr. Leah Chase
Professor of Biology & Chemistry616.395.7375chase@hope.edu
Dr. Leah Chase-Wallar has been at Hope since 2000.
See Dr. Chase-Wallar's current research
AREAS OF INTEREST
- Regulation of cystine/glutamate exchange by system xc-
EDUCATION
- Ph.D., University of Minnesota, 1999
- B.S., University of Michigan ɫɓ Flint, 1993
GRANTS
- Campbell Foundation, ɫɜStudies of the Regulation of System xc¯ Activity in a Dopamergic Cell,ɫɝ 2005ɫɓ2007
- Towsley Research Scholar Program, ɫɜMechanistic and Regulatory Studies of a Neurotransmitter Transport System,ɫɝ 2003ɫɓ2006
- Campbell Foundation, ɫɜRegulation of a Neurotransmitter Transporter by Reactive Oxygen Species,ɫɝ 2003ɫɓ2005
- NSF, ɫɜDevelopment of a project-oriented Neuroscience lab at Hope College,ɫɝ 2002ɫɓ2003
- NSF-CCLI, ɫɜDevelopment of a project-oriented Neuroscience lab at Hope College,ɫɝ 2002ɫɓ2003
- Campbell Foundation, ɫɜMechanistic and regulatory studies of a neurotransmitter transporter,ɫɝ 2001ɫɓ2003
- Campbell Foundation, ɫɜMechanistic and regulatory studies of a neurotransmitter transport system,ɫɝ 2001
- Hope College, Faculty Development Grant, 2001
Published Works
- ɫɜThe Lathyrus Toxin, b-N-oxalyl-L-a,b-diaminoproprionic acid (ODAP) and Homocysteic Acid Sensitize CA1 Pyramidal Neurons to Cystine and L-Amino-6-Phosphonohexanoic Acid,ɫɝ Toxicology and Applied Pharmacology, 219(1), 2007
- ɫɜl-Quisqualic Acid Transport into Hippocampal Neurons by a l-Cystine-Sensitive Carrier is Required for the Induction of l-Quisqualate Sensitization,ɫɝ Journal of Neuroscience, 106(2), 2001
- ɫɜAbolition of Quisqualate Sensitization and Enhancement of Potency for Depolarization by Quisqualate in 24-hour Hippocampal Slices briefly exposed to Quisqualate,ɫɝ Society for Neuroscience, Abst. 26, 2000
- ɫɜDifferentiation of Two Na+-Independent Glutamate Transport Subtypes in Rat Hippocampal Slices,ɫɝ Society for Neuroscience, Abst. 25, 1999
- ɫɜEffects of Quisqualic Acid Analogs on Metabotropic Glutamate Receptors Coupled to Phosphoinositide Hydrolysis in Rat Hippocampus,ɫɝ Neuropharmacology, 34, 1995
- ɫɜType 4a Metabotropic Glutamate Receptor: Identification of New Potent Agonists and Differentiation from the l-(+)2-Amino-4-Phosphonobutanoic Acid Sensitive Receptor in the Lateral Perforant Pathway in Rats,ɫɝ Molecular Pharmacology, 48, 1995
- ɫɜAspects of Nitrogen and Mineral Nutrition in Icelandic Reindeer, Rangifer tarandus,ɫɝ Journal of Comparative Biochemistry and Physiology, 109A, 1994
Outside the College
When sheɫəs not working at Hope, Leah enjoys spending time with her husband, Brad,
and their children. In the summer, they enjoy camping, going to the beach and bike
riding on Mackinac Island.
Dr. Leah Chase
616.395.7375
chase@hope.eduA. Paul Schaap Science Center 3106A 35 East 12th Street Holland, MI 49423-3605